Signaling Pathways for Translation - Insulin and NutrientsPevná vazba
Signaling Pathways for Translation - Insulin and NutrientsPevná vazba The articles in the present volume are by major contributors to our under- standing of signaling pathways affecting protein…
Specifikacia Signaling Pathways for Translation - Insulin and NutrientsPevná vazba
Signaling Pathways for Translation - Insulin and NutrientsPevná vazba
The articles in the present volume are by major contributors to our under- standing of signaling pathways affecting protein synthesis. Insulin is one of the best-studied extracellular regulators of protein syn- thesis. They focus pri- marily on two extracellular anabolic signals, although others are included as well.
Regulation of protein synthesis by amino acids, by contrast, is an emerging field that has recently received a great deal of attention. Several of the known pathways for regulation of protein synthesis were elucidated using insulin-dependent systems. The dual role of amino acids as substrates for protein syn- thesis and regulators of the overall process has only recently been recognized.
Since amino acids serve as precursors for proteins, one might expect that with- holding an essential amino acid would inhibit the elongation phase. Surpris- ingly, research has shown that