Retrotransposons and Human Disease: L1 Retrotransposons as a Source of Genetic Diversity Abram Gabriel
Retrotransposons and Human Disease: L1 Retrotransposons as a Source of Genetic Diversity Abram Gabriel Thirty years ago we knew that retrotransposons made up at least half of our genomes, but little…
Specifikacia Retrotransposons and Human Disease: L1 Retrotransposons as a Source of Genetic Diversity Abram Gabriel
Retrotransposons and Human Disease: L1 Retrotransposons as a Source of Genetic Diversity Abram Gabriel
Thirty years ago we knew that retrotransposons made up at least half of our genomes, but little about their role in biology. However, as of today, the function of retrotransposons still remains elusive. The human genome has since been sequenced and the position of all retrotransposons in the reference sequence has been determined.
This book posits that We know much more about the diseases associated with their movement and the host defenses we all have against them.This volume explores an array of diseases in humans associated with L1 retrotransposon movement within the human genome, including some cancers such as colon cancer and neuropsychiatric disorders such as schizophrenia.The chapters explore the diversity of retrotransposons, their different biological mechanisms, the role of L1 in their movement, and their contribution to human diseases.