Polymorphism in the Pharmaceutical Industry
Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It emphasizes why solid-state issues are important, the approaches needed t… Celý popis ↓
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Polymorphism in the Pharmaceutical Industry
Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues.As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development.
Important analytical tools to The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling.
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