Male Infertility
Male Infertility Male infertility is a multifactorial syndrome encompassing a wide variety of disorders. The causes are known in less than half of these cases, out of which genetic or inherited…
Specifikacia Male Infertility
Male Infertility
Male infertility is a multifactorial syndrome encompassing a wide variety of disorders. The causes are known in less than half of these cases, out of which genetic or inherited disease and specific abnormalities in the Y chromosome are major factors. In more than half of infertile men, the cause of their infertility is mysterious (idiopathic) and could be congenital or acquired.
Molecular genetic techniques have unveiled a number of etiopathogenetic factors, including microdeletions of the Yq. About 10-20 percent of males presenting without sperm in the ejaculate carry a deletion of the Y chromosome Male genetic factor of infertility accounts for about half the cases of couple infertility and in around 50% of cases its etiology remains unknown. Y chromosome microdeletions removing the AZoospermia Factor (AZF) regions are the most frequent molecular genetic causes of