Hepatobiliary Cancers: Translational Advances and Molecular Medicine: Volume 156 Sirica Alphonse C.
Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma ( 75 %…
Specifikacia Hepatobiliary Cancers: Translational Advances and Molecular Medicine: Volume 156 Sirica Alphonse C.
Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma ( 75 % of all cases) and intrahepatic biliary cancer or cholangiocarcinoma ( 10-15 % 0f all cases) is the 6th most commonly diagnosed cancer and 4th leading cause of cancer deaths worldwide. The vast majority of these highly malignant cancers are diagnosed at an advanced stage where treatment options are limited and patient survival outcomes are poor. The biological and therapeutic challenges posed by hepatobililiary cancers such as hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are daunting, emphasizing a critical need to review and assess current and evolving basic, translational, and clinical research focused on addressing the critical obstacles that continue to limit progress