Diagnostic Genetic Testing: Core Concepts and the Wider Context for Human DNA Analysis Bourn David
Diagnostic Genetic Testing: Core Concepts and the Wider Context for Human DNA Analysis Bourn David Chapter 1: Genetic testing, some themes and some basicsBrief introduction to genetic testing.Themeso…
Specifikacia Diagnostic Genetic Testing: Core Concepts and the Wider Context for Human DNA Analysis Bourn David
Diagnostic Genetic Testing: Core Concepts and the Wider Context for Human DNA Analysis Bourn David
Chapter 1: Genetic testing, some themes and some basicsBrief introduction to genetic testing.Themeso Complexity o Risk and uncertainty o DNA and identities o Future promises and limitations - Genetic basics o Information storage and copying o Chromosomes and inheritance patterns o Genes in genomes (nuclear and mitochondrial) o Transcription, translation and the genetic code o Mutation - Basic techniques of genetic testing o DNA extraction o Hybridisation o PCR and DNA amplification o Electrophoresis o DNA sequencingChapter 2: Huntington disease, a severe autosomal recessive disorderHuntington disease (HD)Mutation mechanism and gain of functionTrinucleotide repeat expansionsPenetrance