Adaptive Oncogenesis: A New Understanding of How Cancer Evolves Inside Us Degregori JamesPevná vazba
Adaptive Oncogenesis: A New Understanding of How Cancer Evolves Inside Us Degregori JamesPevná vazba Popular understanding holds that genetic changes create cancer. Cancer is as much a disease of…
Specifikacia Adaptive Oncogenesis: A New Understanding of How Cancer Evolves Inside Us Degregori JamesPevná vazba
Adaptive Oncogenesis: A New Understanding of How Cancer Evolves Inside Us Degregori JamesPevná vazba
Popular understanding holds that genetic changes create cancer. Cancer is as much a disease of evolution as it is of mutation, one in which mutated cells outcompete healthy cells in the ecosystem of the body's tissues. James DeGregori uses evolutionary principles to propose a new way of thinking about cancer's occurrence.
These mechanisms engender a tissue environment that favors normal stem cells over precancerous ones. His theory ties cancer's progression, or lack thereof, to evolved strategies to maximize reproductive success.Through natural selection, humans evolved genetic programs to maintain bodily health for as long as necessary to increase the odds of passing on our genes--but not much longer. Healthy tissues thwart cancer cells' ability to outcompete their precancerous rivals.
But as our tissues age or accumulate damage from exposures such as smoking, normal stem