Poison Trials

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Poison Trials
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Poison Trials

In 1524, Pope Clement VII gave two condemned criminals to his physician to test a promising new antidote. In sixteenth-century Europe, this and more than a dozen other accounts of poison trials were committed to writing. After each convict ate a marzipan cake poisoned with deadly aconite, one of them received the antidote, and lived--the other died in agony.

As doctors created, performed, and evaluated poison trials, they devoted careful attention to method, wrote detailed experimental reports, and engaged with the problem of using human subjects for fatal tests. Alisha Rankin tells their little-known story.At a time when poison was widely feared, the urgent need for effective cures provoked intense excitement about new drugs. In reconstructing this history, Rankin reveals how the antidote trials generated extensive engagement with "experimental thinking" long before the great

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