Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials Kieser Meinhard
Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials Kieser Meinhard This book provides an extensive overview of the principles and methods of sample size…
Specifikacia Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials Kieser Meinhard
Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials Kieser Meinhard
This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. At the same time, a sample size that is too small or too large is problematic due to ethical, scientific, and economic reasons. Appropriate calculation of the required sample size is crucial for the success of clinical trials.
This enables an understanding of the common principles underlying the numerous methods presented in the following chapters. Therefore, state-of-the art methods are required when planning clinical trials.Part I describes a general framework for deriving sample size calculation procedures. Part II addresses the fixed sample size design, where the required sample size is determined in the planning stage and is not changed afterwards.
It covers sample size calculation methods for superiority, non-inferiority, and