Innate Antiviral Immunity - Methods and ProtocolsPevná vazba
Innate Antiviral Immunity - Methods and ProtocolsPevná vazba This book explores methods to study the complex and evolving interplay between a virus and its host that range from model systems to the…
Specifikacia Innate Antiviral Immunity - Methods and ProtocolsPevná vazba
Innate Antiviral Immunity - Methods and ProtocolsPevná vazba
This book explores methods to study the complex and evolving interplay between a virus and its host that range from model systems to the detection of chemical molecules. Subsequent chapters outline diverse methods to detect small interfering RNAs, microRNAs, and virus-derived dsRNA from a variety of cells, tissues, and organisms, as well as to interrogating the cytosolic RNA and DNA sensing pathways, including using RNA PAMPs as molecular tools, purification of cGAMP from virus particles and infected cells, and mechanisms to visualize the subcellular localization and activation of the adaptor proteins MAVS and STING. The collection starts with the application of humanized mice and zebrafish as model organisms to study virus-host interactions and induction of innate immune responses.
Cutting-edge methods, including high-throughput and genome-wide CRISPR/Cas9 screens, chromosome